Multiple Myeloma Kappa Light Chain Prognosis

A lower proportion of kappa lcd patients 15 7 than lambda lcd patients 42 2 died within.

Multiple myeloma kappa light chain prognosis.

Bone lesions seen on mri or pet ct imaging. Light chain myeloma also known as light. When the body detects an infection these white blood cells transform into plasma cells which create proteins called immunoglobulins also known as antibodies. Additional genetic testing of a patient s myeloma cells can be done to determine risk based on common genetic myeloma features.

Light chain multiple myeloma is a type of multiple myeloma a cancer of the plasma cells multiple myeloma begins in the bone marrow where white blood cells are formed. One of the key markers that myeloma doctors pay attention to are 1 the involved light chain for your type of myeloma kappa or lambda and 2 the kappa lambda light chain ratio. Multiple myeloma is a form of cancer that afflicts human bone marrow and blood cells. The second most common type is the iga myeloma also in combination with any of the two light chains.

Ninety seven patients with light chain disease lcd were studied. The light chains are classified as kappa or lambda. The international staging system iss is now used more commonly to classify multiple myeloma. Learn how doctors decide the stage of your cancer and what that means for your recovery.

The plasma cells of myeloma will secrete excess amounts of either of these light chains. Kappa light chain multiple myeloma treatment multiple myeloma is a rare form of cancer that begins in the bone marrow when abnormal plasma cells accumulate and crowd out healthy blood cells. The serum free light chain test can be used to determine light chain levels of disease so patients will want to track their light chain numbers. Learn more about kappa and lambda light chains and multiple myeloma.

When your doctor diagnoses multiple myeloma she will also tell you the stage your disease is in. There are different stages and varieties of this incurable form of cancer and each one produces different symptoms and levels of risk to the patients well being and life. Healthy blood cells produce antibodies that help to fight infection. Each of these immunoglobulins have a light chain like kappa or lambda and a heavy chain like igg iga igm etc.

This means type g immunoglobulin one of the possible types of heavy chain one combination of types of light chain kappa or lambda.